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The story of Breathers follows a small cast of individuals as they struggle to make sense of the dystopian world they live in, as a virus is unleashed into the air, rendering it deadly to humans. Among them: a detective whose addiction to the drug known as "Filter K" takes over his life; a brother and sister who, due to recent events, start to wonder if the air really is deadly, or if it's all just a conspiracy; a mother and daughter who will do anything to keep their family together; and a breather salesman who is looking to make amends for his past mistakes. They are all survivors of this virus-plagued world. They are all "breathers."